Osamu Inanami Selected Research

Mitochondrial Diseases (Mitochondrial Disease)

1/2022	Ubiquitin-Specific Protease 2 in the Ventromedial Hypothalamus Modifies Blood Glucose Levels by Controlling Sympathetic Nervous Activation.
1/2019	Inhibition of ubiquitin-specific protease 2 causes accumulation of reactive oxygen species, mitochondria dysfunction, and intracellular ATP decrement in C2C12 myoblasts.
7/2008	Purvalanol A induces apoptosis and downregulation of antiapoptotic proteins through abrogation of phosphorylation of JAK2/STAT3 and RNA polymerase II.

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Osamu Inanami Research Topics

Disease

35	Neoplasms (Cancer) 07/2022 - 04/2003
10	Carcinoma (Carcinomatosis) 06/2018 - 09/2003
6	Hypoxia (Hypoxemia) 01/2022 - 11/2007
4	Lung Neoplasms (Lung Cancer) 01/2022 - 03/2005
4	Leukemia 01/2011 - 09/2003
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 07/2008
3	Inflammation (Inflammations) 01/2019 - 04/2003
3	Ischemia 01/2007 - 09/2002
3	Brain Injuries (Brain Injury) 01/2007 - 09/2002
2	Hyperglycemia 01/2022 - 05/2008
2	Edema (Dropsy) 10/2021 - 09/2008
2	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2018 - 01/2015
2	Glioblastoma (Glioblastoma Multiforme) 10/2017 - 03/2013
2	Adenocarcinoma 01/2017 - 03/2008
2	Glioma (Gliomas) 03/2013 - 09/2008
2	Infections 05/2008 - 03/2006
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2022
1	Hypoglycemia (Reactive Hypoglycemia) 01/2022
1	Breast Neoplasms (Breast Cancer) 01/2022
1	Osteosarcoma (Osteogenic Sarcoma) 09/2021
1	Myocardial Infarction 07/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 07/2021
1	Stroke (Strokes) 07/2021
1	Atherosclerosis 07/2021
1	Methemoglobinemia 03/2021
1	Pain (Aches) 01/2019
1	Vascular System Injuries 07/2015

Drug/Important Bio-Agent (IBA)

10	Pharmaceutical PreparationsIBA 01/2022 - 07/2005
6	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2021 - 09/2008
4	Biological ProductsIBA 10/2021 - 05/2008
3	LigandsIBA 10/2021 - 11/2007
3	Phosphotransferases (Kinase)IBA 01/2018 - 05/2007
3	Protons (Proton)IBA 01/2016 - 12/2003
3	SurvivinIBA 07/2008 - 05/2007
3	1- (3- C- ethynylribopentofuranosyl)cytosineIBA 05/2007 - 12/2004
3	AntioxidantsIBA 01/2007 - 04/2003
2	Oxygen (Dioxygen)IBA 01/2020 - 10/2017
2	Adenosine Triphosphate (ATP)IBA 01/2019 - 06/2018
2	doranidazoleIBA 02/2018 - 03/2013
2	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 07/2015 - 01/2015
2	Small Interfering RNA (siRNA)IBA 05/2015 - 10/2012
2	DNA (Deoxyribonucleic Acid)IBA 10/2013 - 07/2011
2	Nitric Oxide Synthase (NO Synthase)IBA 08/2013 - 05/2008
2	Proteins (Proteins, Gene)FDA Link 08/2013 - 07/2008
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 08/2013 - 05/2008
2	Insulin (Novolin)FDA Link 02/2010 - 05/2008
2	6- ((3- chloro)anilino)- 2- (isopropyl- 2- hydroxyethylamino)- 9- isopropylpurineIBA 07/2008 - 05/2007
2	LactoferrinIBA 05/2008 - 05/2008
2	BromidesIBA 05/2008 - 09/2003
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2008 - 11/2007
2	Death Domain ReceptorsIBA 03/2008 - 03/2005
2	phenyl-N-tert-butylnitroneIBA 09/2007 - 09/2002
2	Caspase 3 (Caspase-3)IBA 03/2005 - 09/2003
2	malonic acid (malonate)IBA 04/2004 - 09/2002
1	Glutamine (L-Glutamine)FDA Link 07/2022
1	GalactosidasesIBA 07/2022
1	GlutaminaseIBA 07/2022
1	Blood Glucose (Blood Sugar)IBA 01/2022
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2022
1	eribulin FDA Link 01/2022
1	nitroxylIBA 01/2022
1	2- amino- 3- (4- ((5- amino- 2- phenylbenzo(d)oxazol- 7- yl)methoxy)- 3,5- dichlorophenyl)propanoic acidIBA 11/2021
1	AntigensIBA 10/2021
1	AntibodiesIBA 10/2021
1	Therapeutic UsesIBA 10/2021
1	Coloring Agents (Dyes)IBA 10/2021
1	silicon phthalocyanineIBA 10/2021
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 10/2021
1	Metformin (Glucophage)FDA LinkGeneric 09/2021
1	Isoleucine (L-Isoleucine)FDA Link 03/2021
1	NAD (NADH)IBA 03/2021
1	Oxidoreductases (Dehydrogenase)IBA 03/2021
1	EnzymesIBA 03/2021
1	Codon (Codons)IBA 03/2021
1	Leucine (L-Leucine)FDA Link 03/2021
1	Cytochromes b5 (Cytochrome b5)IBA 03/2021
1	Formaldehyde (Formol)FDA Link 01/2019
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019
1	Substance PIBA 01/2019
1	Ubiquitin-Specific ProteasesIBA 01/2019
1	Dinoprostone (PGE2)FDA Link 01/2019
1	NucleotidesIBA 06/2018
1	IronIBA 06/2018
1	SolutionsIBA 01/2018
1	CationsIBA 01/2017
1	HydrocarbonsIBA 01/2017
1	triphenylphosphoniumIBA 01/2017
1	tempolIBA 01/2017
1	NucleosidesIBA 01/2016
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2015
1	polyethylene glycol polyethyleneimine nanogelIBA 05/2014
1	GoldIBA 05/2014
1	Antineoplastic Agents (Antineoplastics)IBA 05/2014
1	Pyruvic Acid (Pyruvate)IBA 05/2014

Therapy/Procedure

9	Therapeutics 11/2021 - 05/2008
9	Radiotherapy 11/2021 - 11/2007
2	Aftercare (After-Treatment) 10/2021 - 07/2005
2	Oral Administration 05/2008 - 01/2007
1	Drug Therapy (Chemotherapy) 01/2019
1	Proton Therapy 01/2016